Homoeopathy and nutritional therapy may offer novel opportunities to improve ADHD

Attention deficit hyperactivity disorder (ADHD) is a lifelong condition associated with considerable costs.

The long-term effectiveness and acceptability of treatments to improve outcomes remains in doubt. Long-term trials are needed comparing interventions with standard care and each other.

The Sheffield Treatments for ADHD Research (STAR) project used the Trials within Cohorts (TwiCs) approach.

A cohort of children with ADHD was recruited and outcomes collected from carers and teachers.

A random selection was offered treatment by homoeopaths (hom) or nutritional therapists (NT).

Their outcomes (Conners Global ADHD Index) were compared with those not offered interventions.

The feasibility of the methods and interventions was assessed. The TwiCs approach was feasible with modifications.

144 participants were recruited to the cohort, 83 offered treatment, 72 accepted, and 50 attended 1+ appointments.

Results according to carers assessments at 6 months were as follows: t?=?1.08, p?=?.28 (-?1.48, 4.81) SMD .425 (hom); t?=?1.71, p?=?.09 (-?.347, 5.89), SMD?=?.388 (NT).

Teachers’ responses were too few and unstable.

No serious treatment adverse events occurred.

Conclusion: the STAR project demonstrated the feasibility of the TwiCs approach for testing interventions for children with ADHD.

What is Known:

• Attention deficit hyperactivity disorder (ADHD) is a lifelong condition associated with considerable costs to ADHD stakeholders. Children are at risk of negative outcomes and in need of pre-emptive strategies

• The long-term effectiveness and acceptability of recommended treatments to improve outcomes remains in doubt

What is New:

• A small-scale test of the design demonstrated that the Trials within Cohorts (TwiCs) approach is feasible and can make a useful contribution regarding testing the effectiveness of interventions for children with ADHD to improve long-term negative outcomes

• Treatment by homoeopaths and nutritional therapists may offer novel opportunities to improve outcomes.


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